What Is NDT?

NDT (natural desiccated thyroid) is one kind of thyroid medication, often deemed the most effective by thyroid patients who have tried both T4-only synthetics such as Levothyroxine or Synthroid as well as  NDT. Thyroid UK did a survey in 2015 which demonstrated that their respondents had the best success rate with NDT.

What is NDT?
NDT contains real thyroid gland, from pigs, and it is available on prescription in the UK on a named-patient basis, as well as meeting the guidelines of the US Pharmacopeia. It is available in most countries through a doctor. It is made according to certain quality standards, contrary to what some doctors say.

How long has NDT been around?
As explained in various books such as Stop The Thyroid Madness’ book and Barry Durrant-Peatfield’s The Great Thyroid Scandal, NDT has been used successfully for over 115 years. Interesting history about its use is mentioned in various books, And I’ve covered it here.

So why is NDT so popular with thyroid patients?
Well, unlike synthetic T4-only medicine such as Levothyroxine and Synthroid,  which have left a lot of patients unwell, NDT is natural and gives you exactly what your own thyroid (if it was healthy!) would be giving you; T1, T2, T3, T4 and Calcitonin.

A lot of patients who’ve tried T4-only medicine, T4 and T3 together, or even just T3 on its own, have reported much better quality of life and elimination of symptoms with NDT. Including myself.

As Thyroid UK report here“Levothyroxine treatment provided total relief of symptoms in 7% of the respondents and significant relief in 41% of respondents. However, 6% of respondents received no relief from symptoms and 40% only slight relief.
NDT provides the most relief of symptoms providing 29% with a total relief of symptoms and 57% with significant improvement. However, 10% only received slight relief and 2% no relief of symptoms.” This is a huge difference. 

What brands are there and which one should I get?
There are many different brands, all of which can viewed here.  One brand is not necessarily better than another, it depends on what works for you. Some people can be allergic to binders or fillers in some.

There is also a bovine desiccated thyroid product available, although far weaker in strength, which patients report needing a lot more of, by Nutri Meds. There is also Dr. Lowe’s ThyroGold, a New Zealand bovine desiccated thyroid.

I must stress here that the ideal situation would be for your doctor to prescribe you this medicine, although I appreciate that for some people, self-sourcing is their only option.

I recommend exploring every avenue possible to have NDT prescribed for you before deciding to go ahead with self-sourcing. Self-sourcing can obviously be risky and dangerous.
How do I change from taking T4-only medicine (like Levothyroxine or Synthroid) to NDT?
Following the STTM protocol, like me, people who switch tend to take their T4-only medicine, e.g. Levothyroxine, a final day, then start on NDT the next day with a safe beginning dose. This is usually one grain, which is raised by half a grain every one to two weeks. When you reach two grains, you start holding each half grain increase for 4-6 weeks until you feel well and have blood tests that read correctly. Stop The Thyroid Madness suggest a suppressed TSH, Free T3 top quarter of the range and Free T4 mid-range or a little higher. You’re also looking for a good pulse rate and healthy body temp, as Durrant-Peatfield explains in his book.

STTM-graphic-When-Optimal-on-NDT-683x1024

Using a mercury thermometer, take readings first thing in the morning before you raise from your bed and look for a healthy before-rising morning basal temp between 97.8 – 98.2 (under the arm for ten minutes). Please see more info here.

You should start to see your temperature climb to healthy levels with feel-good symptoms and good test results to match, as you become optimal on NDT.

So, is NDT the best thyroid medication?

It’s not as simple an answer as you think. The ‘best’ medication is what works best for you, and you feel comfortable with. Synthetic T4, Synthetic T3 and NDT all work well for different patients.


You can read about my experience of changing to NDT here.

I would always suggest working with a doctor where possible and to not make any change to your health regime without consulting a doctor first.

I hope this is helpful to you!

You can click on the hyperlinks in the above post to learn more and see references to information given.

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-Rachel

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